Claire Foy, Charlie Brooker and Thandie Newton are among the British winners at the 70th annual Primetime Emmy Awards.
The ceremony is currently taking place at the Microsoft Theatre in Los Angeles.
Foy took home the best actress in a drama series for her role as Queen Elizabeth II in The Crown.
In her acceptance speech, the actress described her time on the Netflix series as "the most extraordinary two-and-a-half years of my life.
"I was given a role I never thought I would ever get a chance to play, and I met people who I will love for ever and ever.
"And the show goes on, which makes me so proud. So I dedicate this to the next cast, the next generation, and I also dedicate this to [her co-star] Matt Smith."
Olivia Colman is due to take over the role from Foy as the show enters its third season.
Newton was awarded best supporting actress in a drama series for her role in Westworld.
"I don't even believe in God but I'm going to thank her tonight," the actress said as she took to the stage to collect her trophy.
Welsh actor Matthew Rhys, star of The Americans, also picked up the prize for best leading actor in a drama series.
"Parts like these come along so rarely. I will forever be in your debt," he told series creator Joe Weisberg in his speech.
Charlie Brooker, the British creator of Black Mirror and his co-writer William Bridges won best writing for a limited series.
John Oliver added to the British success at the ceremony, picking up the prize for best variety talk series for Last Week Tonight with John Oliver.
The Marvelous Mrs Maisel was one of the night's other biggest winners - adding five trophies to the four it won last week at the Creative Arts Emmys.
The series took home best writing, directing, lead actress and supporting actress in the comedy categories, as well as one of the night's big prizes - best comedy series.
Henry Winkler won his first Emmy - supporting actor in a comedy series for his role in Barry - 42 years after he was first nominated for playing The Fonz in Happy Days.
"Skip Brittenham said to me a long time ago, 'if you stay at the table long enough, the chips come to you,' and tonight I got to clear the table," he said in his acceptance speech.
Jeff Daniels took home the prize for best supporting actor in a limited series or a television movie for his role in Netflix's Godless - described as a feminist western.
In addition to his family and co-workers, Daniels thanked the streaming service for "letting artists be artists".
He added: "Little tip for you young actors - when they call and say 'Can you ride a horse?' don't lie. You will find on day one that you're in the Kentucky Derby."