The firm faces many thousands of lawsuits from consumers who claim that its talc products caused their cancer.
The move comes after years of litigation where Johnson & Johnson has been ordered to pay out billions of dollars in compensation.
The company has consistently defended the safety of its talc products.
Johnson & Johnson said it would wind down sales of the product, which makes up about 0.5% of its US consumer health business, in the coming months, but that retailers would continue to sell existing inventory.
