Smith was a late scratching for the Highlanders last weekend after suffering a hamstring strain during the warmups.
He had previously missed two games with concussion.
Squire has been out of action since suffering a knee injury in the second round in early March.
Preparing for what will no doubt be a physical encounter coach Tony Brown has restored Daniel Lienert-Brown, Siosuia Halanukonuka, Alex Ainley and Elliot Dixon to the starting eight.
Squire makes his return after four weeks on the sideline and will make an impact from the bench.