A study of more than 2,000 young men in India showed more who had coronary artery disease were prematurely bald or grey than men with a full head of hair.
The European Society of Cardiology's study will be read at the Cardiological Society of India's annual conference.
But the British Heart Foundation said other risk factors were important.
Dr Mike Knapton, associate medical director at the BHF, told the BBC: "This study suggests that identifying men with premature hair loss and greying may help identify those with an increased risk of developing heart disease.
