Hillary Rodham Clinton

VIDEO: Hillary Clinton: Cuba embargo must go

The position, which Clinton has already outlined in her 2014 book "Hard Choices," puts her in line with President Barack Obama, who moved in December to establish diplomatic relations with Cuba and has called for normalized trade relations.

Perhaps more importantly, it draws a sharp contrast with two top Republican presidential contenders from Florida, Senator Marco Rubio and former Governor Jeb Bush, at a time when younger Cuban-American voters in Florida are softening their stance on the matter.