Police allege Solomone Taufeulungaki was stabbed after he was approached by a group of up to 10 males outside Brimbank Shopping Centre in Deer Park just after 4:00pm on Tuesday.
ABC News reports the 15-year-old died at the scene.
Six boys aged between 13 and 16 were charged with violent disorder and affray and appeared in a children's court on Wednesday.
Many of them were supported by parents and most of the children will apply for bail in the coming days.