The Pacific Nations Cup holders pipped the Azzurri 22-19 in Suva earlier this year, with first five Ben Volavola slotting an 80th minute drop-goal to secure a dramatic victory.
Fiji also prevailed when the teams met in Suva three years ago but have only managed one win from five tests on Italian soil, way back in 1999.
Coach John McKee believes they have a real opportunity.
