Dane Coles injured a rib in the Hurricanes 41-nil win over the Sharks, while Chiefs co-captain Sam Cane took a knock to the head in their 60 points to 21 win over the Stormers.
Hurricanes coach Chris Boyd isn't confident about Coles' chances of playing.
"He's got a rib injury and is in a lot of pain so the doctor will do whatever he can and we should know more in the next 24 hours, but it doesn't look good."
However Boyd feels good about the cover they have at hooker.