They have built an Earth-sized "virtual telescope" by linking a large array of radio receivers - from the South Pole, to Hawaii, to the Americas and Europe.
There is optimism that observation to be conducted during 5-14 April could finally deliver the long-sought prize.
In the sights of the so-called "Event Horizon Telescope" will be the monster black hole at the centre of our galaxy.
Although never seen directly, this object, catalogued as Sagittarius A*, has been determined to exist from the way it influences the orbits of nearby stars.
