The Forrest Gump and Cast Away actor said the technology could be used to recreate his image, ensuring he continued to appear in movies "from now until kingdom come".
But he admitted the developments posed artistic and legal challenges.
BBC reports his remarks came as the Pet Shop Boys' Neil Tennant said AI could be used by musicians to complete songs.
Hanks, 66, was asked about the legal ramifications of the new technology in the latest episode of The Adam Buxton podcast.
"This has always been lingering," he said. "The first time we did a movie that had a huge amount of our own data locked in a computer - literally what we looked like - was a movie called The Polar Express.
"We saw this coming, we saw that there was going to be this ability to take zeros and ones from inside a computer and turn it into a face and a character. That has only grown a billion-fold since then and we see it everywhere."
The Polar Express, released in 2004, was the first film entirely animated using digital motion-capture technology.
Hanks said talks are being held in the film industry about how to protect actors from the effects of the technology.
"I can tell you that there is discussions going on in all of the guilds, all of the agencies, and all of the legal firms in order to come up with the legal ramifications of my face and my voice and everybody else's being our intellectual property," Hanks added.
"What is a bona fide possibility right now is, if I wanted to, I could get together and pitch a series of seven movies that would star me in them in which I would be 32 years old from now until kingdom come.
"Anybody can now recreate themselves at any age they are by way of AI or deep fake technology. I could be hit by a bus tomorrow and that's it, but performances can go on and on and on and on.
"Outside the understanding of AI and deep fake, there'll be nothing to tell you that it's not me and me alone.
"And it's going to have some degree of lifelike quality. That's certainly an artistic challenge but it's also a legal one."