The competition will be seeded into two conferences based on the previous season standings.
The round robin will also include four crossover matches between the two conferences.
The quarterfinals include the top four teams within each conference playing for a spot in the semi-finals.
With the top two teams across the conferences playing against each other in the semi-finals, to then see the top two qualifiers play off in the NPC final.
NZR Head of Community Rugby Steve Lancaster said:
"NZR made the decision in consultation with the Provincial Unions to review the existing Bunnings NPC Premiership and Championship format following last season. The consultation process has been extensive, with a range of options considered and all key stakeholders included."
"We are pleased with where the competition format has landed, shifting to a single national championship with seeded pools based on the previous year's performance provides for evenly balanced conferences and strong competition to qualify for the play-offs. Any team can now be crowned national champion, which is exciting not only for teams but also our wider rugby community who support them."
The NPC will be played over 12 weeks from 5 August, with the inclusion of a mid-week round for all teams. All competition matches carry full competition points and the full draw will be released in due course.
The Ranfurly Shield remains unchanged and is automatically contested when the holder of the shield plays at home in any round, excluding quarterfinals, semi-finals, and finals.