Tyson, the first heavyweight to hold the WBA, WBC and IBF titles, has released several training videos of his own in recent weeks, with the most recent on Monday ending with the message, "I'm back".
The 53-year-old Tyson fought two epic bouts with the 57-year-old Holyfield during their professional careers, including their controversial 1997 encounter in which Tyson bit off a chunk of Holyfield's ear.
"My first week back in the gym and I feel great," Holyfield, the only four-time heavyweight champion in boxing history, said.