In another series first, Adelaide will host a match for the first time, with the players flying in from Queensland and NSW on the day of the game.
The game is expected to be a sell-out, with a COVID-capped crowd of 26,500 in attendance.
Winners of the last two series, New South Wales are clear favourites to make it a hat-trick this year.
The Blues line-up features some of the biggest names in the game, with coach Brad Fittler jamming his team with a range of experienced, high-quality players.
