The former back rower was at home when three people broke into his family home in Coorparoo at 3am on Monday morning.
According to Channel 7, Kefu was stabbed in the stomach after the family confronted the men and a brawl erupted.
Seven ambulance crews attended the scene and he was rushed to Princess Alexandra Hospital and is in a serious condition with abdominal wounds.
He has been in surgery all morning.
Kefu’s wife, son and daughter were injured during the frenzy and were also taken to hospital.